Disintegration test to measure lot-to-lot variations of vaginal tablets.

More on lot-to-lot changes.

Lot-to-lot variations in a qualitative lateral-flow immunoassay for chronic pain drug monitoring.

Recently, Algeciras-Schimnich et al. highlighted the lot-to-lot variability of a quantitative immunoassay and the failure of frequently used protocols to detect these variations (1). We have discovered that lot-to-lot variations also present an important issue in qualitative immunoassays used for chronic pain monitoring. These variations impact the reliability of these assays in clinical practi...

How to Use MRP in Continuous Production Industries When Order Type is Lot for Lot

The Materials Requirements Planning (MRP) method that is applied in production planning and management has some weaknesses. One of its weaknesses is that the time in MRP method is discrete, and is considered as time period. Hence we are not able to order our requirements at irregular time moments or periods. In this paper, a new form of MRP is introduced that is named Continuous Materials Requi...

From Parking Lot to Paradise.

Failure of current laboratory protocols to detect lot-to-lot reagent differences: findings and possible solutions.

BACKGROUND Maintaining consistency of results over time is a challenge in laboratory medicine. Lot-to-lot reagent changes are a major threat to consistency of results. METHODS For the period October 2007 through July 2012, we reviewed lot validation data for each new lot of insulin-like growth factor 1 (IGF-1) reagents (Siemens Healthcare Diagnostics) at Mayo Clinic, Rochester, MN, and the Un...